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Science

Women on The Pill Are 23% More Likely to Be Treated For Depression

Edmund Ayitey
Last updated: February 17, 2025 5:32 am
Edmund Ayitey
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When it comes to birth control, most people focus on the physical benefits—preventing unwanted pregnancy, regulating periods, and reducing acne.

But what if I told you that the very thing protecting you from pregnancy could also be silently reshaping your mental health?

A groundbreaking study has revealed something startling: women on hormonal contraceptives, like the pill or IUDs, have a significantly higher risk of depression.

Even more concerning, this risk skyrockets for teenagers, with some experiencing an 80% increase in their likelihood of being prescribed antidepressants.

And if you’re using a hormonal IUD or certain other birth control methods? That risk triples.

The findings, which come from the University of Copenhagen in Denmark, challenge the assumption that birth control only affects reproductive health.

In reality, it may have a profound impact on mood, emotions, and overall mental well-being.

With millions of women around the world using hormonal contraceptives, this study raises serious questions about how these medications are influencing our brains.

The Science Behind the Risk

The research tracked over 1 million women aged 15 to 34 between the years 2000 and 2013.

Using Denmark’s national healthcare database, scientists analyzed prescriptions and mental health diagnoses, allowing them to pinpoint the relationship between hormonal birth control and depression.

Among those using hormonal contraception, the risk of being diagnosed with depression increased by at least 20% across the board.

Here’s a breakdown of the most affected groups:

  • Women on the pill had a 23% higher chance of being prescribed antidepressants.
  • Mini-pill users (progesterone-only) saw a 34% increase in depression risk.
  • Teenage girls on the pill had an 80% higher chance of developing depression.
  • Teenage girls using other hormonal contraceptives (IUDs, implants, patches) saw their risk double or even triple.

These statistics suggest a direct link between birth control and mental health issues.

But does this mean hormonal contraception is causing depression—or is something else at play?

Challenging the Common Narrative

For decades, doctors and researchers have debated the psychological effects of birth control.

Many dismissed anecdotal reports of mood swings and depression as coincidental or unrelated to the pill itself.

But this new study, the largest of its kind, provides compelling evidence that the link may be real.

Interestingly, past research has yielded mixed results:

  • A 2010 study found only a minor connection between birth control and mood changes.
  • A 2007 study claimed there was no effect at all.
  • A 2011 study suggested that hormonal contraceptives actually improved mood in some cases.

So, what’s really going on? Could it be that certain women are more vulnerable to these effects, or is birth control fundamentally altering brain chemistry?

The answer isn’t entirely clear—but what is clear is that more research is desperately needed.

A Missing Piece of the Puzzle?

Hormonal contraceptives work by altering estrogen and progesterone levels in the body, preventing ovulation.

But these hormones do more than just control reproduction—they play a critical role in regulating mood and behavior.

Dr. Catherine Monk, a psychiatrist at Columbia University Medical Center, points out that the strongest link between depression and birth control appears in teenagers.

She speculates that this may be due to the sensitive nature of adolescent brain development.

“The possibility that this link between love, sex (contraception), and feeling depressed is strengthened by the fact that the contraception-depression link was strongest in adolescents,” Monk told the Huffington Post. “

This is the developmental stage where trying to find a romantic partner is paramount.”

In other words, hormonal birth control might be interfering with a crucial stage of emotional and psychological growth.

And if that’s true, it could have long-term consequences that extend far beyond the teenage years.

What Should Women Do?

Before you toss your birth control in the trash, take a deep breath.

This study doesn’t prove that hormonal contraceptives directly cause depression—only that there’s a strong association.

That means other factors, such as preexisting mental health conditions, lifestyle, or relationship stress, could also be contributing to the increased rates of depression among birth control users.

Dr. Channa Jayasena, a reproductive endocrinologist from Imperial College London, agrees that the findings are significant but warns against drawing premature conclusions.

“This study raises important questions about the pill,” he told The Guardian.

“However, we know hormones play a hugely important role in regulating human behavior.

Further work is needed to see if these results can be repeated in other populations, and to determine possible biological mechanisms which might underlie any possible link between the pill and depression.”

So, what should you do if you’re on birth control and experiencing mood changes?

Practical Steps to Protect Your Mental Health

  1. Monitor Your Mood: Keep a journal of how you feel daily. If you notice persistent sadness, anxiety, or loss of motivation after starting birth control, it could be worth discussing with a doctor.
  2. Explore Alternatives: Not all contraceptives are hormone-based. Barrier methods (condoms, diaphragms) and non-hormonal IUDs (like the copper IUD) provide effective birth control without altering your hormones.
  3. Talk to a Professional: If you’re experiencing depressive symptoms, consult both a gynecologist and a mental health professional. A team approach can help determine the best course of action.
  4. Lifestyle Adjustments: Diet, exercise, sleep, and stress management play a huge role in mental well-being. Even if you stay on hormonal birth control, supporting your mental health with positive lifestyle choices can make a difference.

Final Thoughts: Knowledge is Power

The relationship between birth control and mental health is more complex than we once believed.

While hormonal contraceptives are a life-changing innovation for millions, they aren’t one-size-fits-all—and for some women, they could come with unexpected psychological side effects.

The key takeaway? Stay informed, listen to your body, and don’t be afraid to ask questions.

If you feel different since starting birth control, it’s not “all in your head”—it’s something worth taking seriously.

After all, your mental health is just as important as your reproductive health.

Don’t let outdated assumptions stand in the way of making the best choice for your body and mind.

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