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Science

Study of 95,000 children finds no link Between MMR vaccines and autism

Richard A.
Last updated: April 23, 2025 9:42 pm
Richard A.
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Here’s a truth bomb: children with a genetic risk for autism are not at increased risk of developing the condition after receiving the MMR vaccine.

That’s not speculation—it’s the result of a study involving over 95,000 kids, including nearly 2,000 with older siblings on the autism spectrum.

And the findings? Unmistakably clear.

Published in the Journal of the American Medical Association, this landmark research confirms—yet again—that there’s no link between the MMR (measles, mumps, and rubella) vaccine and autism spectrum disorder (ASD).

Not even in the most vulnerable group: children with a familial predisposition.

This isn’t just another study in a vacuum; it’s one of the most comprehensive assessments to date, zeroing in on a question that’s haunted headlines and parental Facebook groups for decades.

And let’s not forget: this isn’t just about science.

It’s about protecting real children from very real diseases—measles, mumps, and rubella aren’t fairy tales from a bygone era.

In 2014 alone, 288 cases of measles were reported in the US, despite its declared elimination back in 2000.

Those outbreaks?

Direct consequences of falling vaccination rates.

So why does this debate still exist?


Why Are We Still Arguing About This?

Here’s where it gets uncomfortable.

Despite two decades of evidence, including dozens of large-scale studies, a vocal minority still clings to the debunked idea that vaccines cause autism.

This belief persists even though the original 1998 paper that suggested the link has been fully retracted—and its author discredited.

But there’s a deeper, more troubling trend here: fear is winning over fact.

This latest study, led by pediatrician Dr. Anjali Jain from the Lewin Group, takes that fear head-on.

It’s the first to specifically assess whether the MMR vaccine increases autism risk in children who already have a higher genetic predisposition—those with older siblings diagnosed with ASD.

And the result?

“Even in these cases, the data showed no increased risk of ASD related to the MMR vaccine.”

Let’s say that again. No. Increased. Risk.

That’s not a small deal.

It’s a decisive strike against one of the most enduring public health myths of our time.

And it reveals something most of us don’t want to admit: once misinformation gets emotional, it’s almost immune to evidence.


The High Stakes of Vaccine Hesitancy

In Australia, the government responded with policy: beginning in 2016, parents who refuse to vaccinate their children lose access to childcare and welfare benefits.

The reason?

More than 39,000 kids missed essential immunizations under the now-scrapped “conscientious objection” loophole.

The US tells a similar story.

While national vaccination rates remain high on average, they’re slipping in certain regions, especially where misinformation thrives.

Measles cases are up.

Pertussis—better known as whooping cough—has surged by 24% in some areas.

And among families living with autism?

A tragic feedback loop is emerging.

According to Jain’s study, almost 20% of parents with an older child diagnosed with ASD chose not to vaccinate their younger children.

A Canadian study cited by the team found a similar pattern: siblings of children with autism were significantly less likely to be fully vaccinated.

That fear is not just speculative anymore—it’s measurable. And it’s putting lives at risk.


The Data That Should End the Debate

Let’s dive into the numbers.

Out of the 95,727 children examined, 1,929 had older siblings with ASD.

Across the entire cohort, 994 kids (about 1.04%) were diagnosed with ASD during the study period.

Among those with an older sibling on the spectrum, the rate was predictably higher—6.9% compared to 0.9% for those without.

But here’s the clincher: vaccination didn’t change that risk. Not one bit.

“We found no evidence that receipt of either one or two doses of MMR vaccination was associated with an increased risk of ASD among children who had older siblings with ASD,” the authors write.

And not only was there no link, but the vaccination rate itself was notably lower among the high-risk group:

  • At age 2, 84% of children without an ASD sibling were vaccinated, compared to only 73% of those with an ASD sibling.
  • By age 5, the rates improved, but the gap remained: 92% vs. 86%.

Fear had an impact.

And it wasn’t based on science.


This Isn’t Just About Autism Anymore

What we’re dealing with is larger than a single health scare.

This is about the future of evidence-based medicine.

In the early 2000s, the Institute of Medicine examined this same issue, combing through all available epidemiological evidence.

They found nothing. In 2011, they revisited eight major vaccines, MMR included. Still nothing.

Even thimerosal—the mercury-containing compound once suspected of causing autism—has been cleared by at least nine separate international studies.

“We stopped even counting pro-thimerosal papers,” journalist Joshua A. Krisch quipped, “after nine studies from several countries proved that the mercury-containing chemical was entirely safe.”

And now this—an even more comprehensive investigation that not only reaffirms all previous conclusions but does so in the most genetically vulnerable group.

As Bryan King, a psychiatrist at the University of Washington (unaffiliated with the study), puts it:

“Some dozen studies have shown that the age of onset of ­autism spectrum disorders does not differ between vaccinated and unvaccinated children, the severity does not differ, and now the risk of recurrence in families does not differ… the only conclusion is that there is no signal to suggest a relationship with autism.”

It’s not just overwhelming—it’s conclusive.


So What Happens Now?

If we’re being honest, this isn’t just about changing minds.

It’s about rebuilding trust.

Because science alone won’t win this battle—trust will.

Doctors and researchers have done their part.

The evidence is in.

But the challenge now lies with public health officials, teachers, journalists, and yes—parents.

We need to share this data widely, speak plainly, and engage respectfully.

Because if even one parent still feels unsure about vaccinating a child, despite this mountain of evidence, the cost could be another outbreak.

And those outbreaks don’t just impact one family.

They spread.

They take root in the most vulnerable corners of our communities—infants, immunocompromised kids, cancer patients, and the elderly.

Vaccination isn’t a personal choice.

It’s a collective responsibility.


It’s Time to Move On

Let researchers study something else.

Let’s redirect our energy to improving early autism interventions, understanding its genetic roots, and developing better support systems for families living with ASD.

Let’s stop chasing shadows.

Because at this point, the only thing more contagious than measles is misinformation. And if we’re serious about protecting the next generation, we can’t afford to give it any more air.


Sources:
ABC News, The Journal of the American Medical Association, Vocativ, The Australian, National Journal.


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